603 E 69th St Savannah, GA 31405 | P: 912-629-0444 | F: 912-629-0443

Monday-Friday: 9:00 a.m.-6:30 p.m. | Saturday-Sunday: Closed

*Note: Closed daily for lunch from 1:15-1:45 p.m.*

Pain Management and CBD

September 2020

Pain Awareness Month

Since 2001, each September is Pain Awareness Month. Chronic pain is defined as “pain that continues a month or more beyond the usual recovery period for an injury or illness or that goes on for months or years due to a chronic condition. The pain is usually not constant but can interfere with daily life at all levels.”

In many cases, opioids are prescribed to treat short-term pain. However, many people taking opioids like hydrocodone for a long period of time find themselves heading down a dark road of addiction through no fault of their own. According to the CDC, over 53 million people aged 12 years or older reported use of illicit drugs or misuse of prescription drugs in 2018. Doctors and patients alike are looking for alternatives to relieve pain without the worry of addiction. An alternative that is showing lots of promise is CBD (cannabidiol).

Let’s learn more about CBD!

What is CBD?

CBD is a non-psychoactive cannabinoid. CBD also may have numerous benefits, such as anti-inflammatory and neuroprotective properties.

Cannabinoids are the chemicals that give the cannabis plant its medical and recreational properties. Among the 113 cannabinoids produced, THC and CBD are the most prevalent and the most well-understood. Most strains of marijuana sold today are cultivated with higher levels of THC. THC is known for its psychoactive properties and is the reason you feel “high” after ingesting marijuana. Since CBD is non-psychoactive, it will not produce a “high.”

The human body has an endocannabinoid system (ECS) that receives and translates signals from cannabinoids. It produces some cannabinoids of its own, which are called endocannabinoids. The ECS helps to regulate functions such as sleep, immune-system responses, and pain. CBD is thought to stimulate certain receptors to reduce pain, anxiety, and inflammation It stops the breakdown of anandamide a chemical often referred to as the bliss molecule in your brain. This allows anandamide to stay in your system longer, helping relieve pain and boost brain function CBD also regulates the production of inflammatory molecules called cytokines,thereby reducing inflammation and pain.

What is the Endocannabinoid System (ECS)?

The Endocannabinoid System (ECS) is responsible for maintaining balance, or homeostasis, and optimizing health across biological systems.

The ECS is a neurotransmitter system is made up of CB1 and CB2 receptors throughout the body. Its role is to keep things in the body functioning normally and to keep things in balance. These cell receptors are found in many locations, including the brain, spinal cord and immune system, which give the body instructions on what to do to function properly.

Plant derived cannabinoids (phytocannabinoids) help supplement our Endocannabinoid system when our bodies do not naturally make enough.

Photo: https://globalcannabinoids.io/the-human-endocannabinoid-system/

What are phytocannabinoids?

Phytocannabinoids are plant derived cannabinoids. The flower of the hemp plant contains many different phytocannabinoids. These are turned into hemp extract (commonly known as CBD), which work at the cannabinoid (CB) receptor sites.

What is the difference between CBD/Hemp and THC?

Hemp and marijuana are both part of the Cannabis sativa family. Hemp is federally legal and has low levels of THC (must be less than 0.3% to be legal) while marijuana is not federally legal and has much higher levels of THC (5-35%).

Is CBD legal?

Yes. The 2018 Farm Bill clarified the definition of hemp to include the entire plant, specifically the floral parts and cannabinoids derived from it. It is now exempt from the definition of the controlled substance act (CSA).

Why would someone take Hemp extract oil products?

According to recent research, out of the 62 percent of people who use CBD to treat a medical condition, most use it to manage chronic pain,

arthritis and joint pain. It can also be used to reduce anxiety and help you sleep better.

What types of Hemp oil are available?

You'll find three main types of CBD on the market:

Isolate contains only CBD, with no other cannabinoids.

Full-spectrum contains all cannabinoids naturally found in the cannabis plant, including THC.

Broad-spectrum contains multiple cannabinoids naturally found in the cannabis plant, but doesn't contain THC.

For ultimate therapeutic value, you will want a full-spectrum hemp extract. Unlike isolate products that only contain the isolated molecule, CBD, full-spectrum means the product has CBD, other active cannabinoids, terpenes, flavonoids, omega-3s and omega-6s that naturally occur in the plant. Also, full-spectrum allows for the “entourage effect,” in which the compounds work synergistically to promote a greater response at a lower dose. In fact, research supports that full-spectrum CBD is more effective than isolate CBD.

Are there any side effects associated with CBD?

CBD products are generally well-tolerated. But, according to a review in Cannabis and Cannabinoid Research, the most common side effects include:



changes in appetite

weight gain or weight loss

What should I be looking for to ensure I’m purchasing a quality product?

Certificate of Analysis (CoA or C of A) - any reputable company will provide a third-party analysis that will detail what’s specifically in the bottle.

Check for Chemicals, Pesticides, and Dangerous Additives - You’ll want to make sure the CoA tests for microbes, herbicides, etc. Next to each of those names, look for the result of “ND” or “Not Detected.”

Trusted source - Purchasing CBD from a pharmacy allows you to speak with a pharmacist about the product, how to dose CBD, and check for any potential drug interactions.

How do I compare different CBD brands?

If you’re doing a price comparison, make sure you’re comparing milligrams of active cannabinoids, not just milligrams of oil.

What types of products are available at Compounding Solutions?

● Full Spectrum Extract Oil Tincture

● THC-Free Oil Tincture

● Capsules

● THC-Free Capsules

● Salve

● Roll-on

● Lotion

● Gummies

● Cream

CBD Consultation

Are you interested in CBD but unsure of where to start? Ask our pharmacists! They are here to help you decide which product would be best, how to dose the medication, and check to any possible drug interactions.

For more questions, please contact us at 912-629-0444, option 3.

Are you looking for more information on how to use CBD? Read our post on how to use CBD, dosing, and using our toolkit for success.